A 25-year-old woman with advanced cervical cancer died of another condition which developed, an inquest heard.
Paige Alexandra Hart was diagnosed at the age of 24 in November 2018.
She started chemotherapy and radiotherapy and had a good response to initial treatment.
But then she was admitted to hospital with right-sided abdominal pain and was found to have incurable metastatic cancer, and Paige had suffered a relapse. Again she had a good response to treatment.
She was admitted to hospital as an emergency with new lower abdominal pain and her abdominal symptoms became worse and a scan revealed perforated colitis.
An inquest in Nottingham heard the condition which led to her death was fecal peritonitis as a result of bevacizumab-induced colitis with colonic perforation.
Bevacizumab is a medication which is used to treat a number of cancers, and a necessary treatment for cervical cancer which could be life-prolonging.
Paige died on April 24 this year at City Hospital.
Paige had an urgent CT scan in the middle of the night which showed a lot of air in the abdomen, which was a sign of bowel perforation.
Conservative management was recommended, a case of wait and watch to see what happens next and sometimes patients can recover, the inquest heard.
Over the next couple of weeks Paige was reviewed on a daily basis, explained a consultant clinical oncologist employed by Nottingham University Hospitals NHS Trust.
Giving evidence from a virtual link to the coroner in the Council House, she explained how Paige was kept on antibiotics and, at one point, it was felt she turned a corner and felt better.
But she began to deteriorate over the coming weeks and “this was a gradual decline in her general condition”, said the consultant.
When she saw Paige again, she was not very well and, at that time, put on an end of life care pathway.
Assistant coroner Fiona Gingell asked her: “Having reviewed matters, is there anything, in your professional opinion, which could have been done differently for Paige around her treatment?”
The consultant replied: “I don’t think so”.
After giving evidence, the consultant addressed Paige’s mother, who attended on a virtual link with Paige’s aunt and uncle, and she said; “I’m so sorry what happened to Paige. We couldn’t have predicted it”.
The coroner concluded a narrative verdict.
She said the Bevacizumab was a necessary treatment to treat the cervical cancer and this was a “life-prolonging treatment”.
The coroner offered her sincere condolences to Paige’s family and described it as a “sad set of circumstances and a tragic event for someone so young”.